IEEE International Symposium on Applications of Ferroelectrics, ISAF 2023, International Symposium on Integrated Functionalities, ISIF 2023 and Piezoresponse Force Microscopy Workshop, PFM 2023, Proceedings
Radio frequency (RF) magnetic devices are key components in RF front ends. However, they are difficult to miniaturize and remain the bulkiest components in RF systems. Acoustically driven ferromagnetic resonance (ADFMR) offers a route towards the miniaturization of RF magnetic devices. The ADFMR literature thus far has focused predominantly on the dynamics of the coupling process, with relatively little work done on the device optimization. In this work, we present an optimized 2 GHz ADFMR device utilizing relaxed SPUDT transducers in lithium tantalate. We report an insertion loss of -13.7 dB and an ADFMR attenuation constant of -71.7 dB/mm, making this device one of the best performing ADFMR devices to date.
The purpose of this effort is to investigate whether large acoustic pressure waves can be transmitted inside beverage containers to enable pasteurization. Acoustic waves are known to induce large nonlinear compressive forces and shock waves in fluids, suggesting that compression waves may be capable of damaging bacteria inside beverage containers without appreciably increasingly the temperature or altering the freshness and flavor of the beverage contents. Although a combined process such as thermosonication (e.g., sonication with heating) is likely more efficient, it is instructive to compute the acoustic pressure field distribution inside the beverage container. The COMSOL simulations used two and three-dimensional models of beverage containers placed in a water bath to compute the acoustic pressure field. A limitation of these COMSOL models is that they cannot determine the bacterial lysis efficiency, rather the models provide an indirect metric of bacterial lysis based on the magnitude of the pressure field and its distribution.
Epitaxial lithium niobate (LNO) thin films are an attractive material for devices across a broad range of fields, including optics, acoustics, and electronics. These applications demand high-quality thin films without in-plane growth domains to reduce the optical/acoustical losses and optimize efficiency. Twin-free single-domain-like growth has been achieved previously, but it requires specific growth conditions that might be hard to replicate. In this work, a versatile nanocomposite-seeded approach is demonstrated as an effective approach to grow single-domain epitaxial lithium niobate thin films. Films are grown through a pulsed laser deposition method and growth conditions are optimized to achieve high-quality epitaxial film. A comprehensive microstructure characterization is performed and optical properties are measured. A piezoelectric acoustic resonator device is developed to demonstrate the future potential of the nanocomposite-seeded approach for high-quality LNO growth for radio frequency (RF) applications.
We have made significant progress toward the development of an integrated nucleic acid amplification system for Autonomous Medical Devices Incorporated (AMDIs) Optikus handheld diagnostic device. In this effort, we developed a set of loop-mediated isothermal amplification (LAMP) primers for SARS-CoV-2 and then demonstrate amplification directly on a surface acoustic wave (SAW) sensor. We built associated hardware and developed a C-code to control the amplification process. The goal of this project was to develop a nucleic amplification assay that is compatible with SAW sensors to enable both nucleic and serological testing in a single handheld diagnostic device. Toward this goal, AMDI is collaborating Sandia National Laboratories to develop a rapid, portable diagnostic screening device that utilizes Sandias unique surface acoustic wave biosensor (SAW) for COVID-19 detection. Previously, the SANDIA- AMDI SAW sensor has successfully detected multiple high-profile bacteria viruses, including Ebola, HIV, Sin Nombre, and Anthrax. Over the last two years, AMDI and SANDIA have significantly improved the sensitivity and detection capability of the SAW biosensor and have also developed a modular hand-held, portable platform called the Optikus, which uses CD microfluidics and handheld instrumentation to automate all sample preparation, reagent introduction, sample delivery, and measurement for a number of different assay targets. We propose to use this platform for the development of a rapid (%3C30 minutes), point-of-care diagnostic test for detection of COVID-19 from nasal swab samples.
IFCS-ISAF 2020 - Joint Conference of the IEEE International Frequency Control Symposium and IEEE International Symposium on Applications of Ferroelectrics, Proceedings
A true series resonance oscillator has been developed for use with a wide-range of 1-port resonance-based sensors and devices. The oscillator effectively removes the shunt capacitance Co, allowing the true series resonance to be monitored, providing the optimum sensitivity across a wide range of frequencies (i.e. kilohertz to gigahertz), shunt capacitances, and quality factors (Q) for the first time. It is well-known that non-zero shunt capacitance alters the impedance by shifting the location of the impedance minimum and the zero-phase crossing while causing significant impedance distortion. We have developed an active shunt capacitance cancelling oscillator (ASSCO) that removes any shunt capacitance across the resonator by supplying the circuit an equal 'dummy' capacitance using a cancelling current. The oscillator does not require automatic gain control (AGC) and the resonator can be grounded to reduce parasitic contributions.
Sandia National Laboratories currently has 27 COVID-related Laboratory Directed Research & Development (LDRD) projects focused on helping the nation during the pandemic. These LDRD projects cross many disciplines including bioscience, computing & information sciences, engineering science, materials science, nanodevices & microsystems, and radiation effects & high energy density science.
Electric field-based frequency tuning of acoustic resonators at the material level provides an enabling technology for building complex tunable filters. Tunable acoustic resonators were fabricated in thin plates (h/λ ∼ 0.05) of X-cut lithium niobate (90°, 90°, ψ = 170°). Lithium niobate is known for its large electromechanical coupling (SH: K2 40%) and thus applicability for low-insertion loss and wideband filter applications. We demonstrate the effect of a DC bias to shift the resonant frequency by 0.4% by directly tuning the resonator material. The mechanism is based on the nonlinearities that exist in the piezoelectric properties of lithium niobate. Devices centered at 332 MHz achieved frequency tuning of 12 kHz/V through application of a DC bias.
Miniature ultrasonic lysis for biological sample preparation is a promising technique for efficient and rapid extraction of nucleic acids and proteins from a wide variety of biological sources. Acoustic methods achieve rapid, unbiased, and efficacious disruption of cellular membranes while avoiding the use of harsh chemicals and enzymes, which interfere with detection assays. In this work, a miniature acoustic nucleic acid extraction system is presented. Using a miniature bulk acoustic wave (BAW) transducer array based on 36° Y-cut lithium niobate, acoustic waves were coupled into disposable laminate-based microfluidic cartridges. To verify the lysing effectiveness, the amount of liberated ATP and the cell viability were measured and compared to untreated samples. The relationship between input power, energy dose, flow-rate, and lysing efficiency were determined. DNA was purified on-chip using three approaches implemented in the cartridges: a silica-based sol-gel silica-bead filled microchannel, nucleic acid binding magnetic beads, and Nafion-coated electrodes. Using E. coli, the lysing dose defined as ATP released per joule was 2.2× greater, releasing 6.1× more ATP for the miniature BAW array compared to a bench-top acoustic lysis system. An electric field-based nucleic acid purification approach using Nafion films yielded an extraction efficiency of 69.2% in 10 min for 50 μL samples.
A comparison study between Y + 36°and 0°X-cut lithium niobate (LiNbO3) was performed to evaluate the influence of crystal cut on the acoustic propagation to realize a piezoelectric high-voltage sensor. The acoustic time-of-flight for each crystal cut was measured when applying direct current (DC), alternating current (AC), and pulsed voltages. Results show that the voltage-induced shift in the acoustic wave propagation time scaled quadratically with voltage for DC and AC voltages applied to X-cut crystals. For the Y + 36°crystal, the voltage-induced shift scales linearly with DC voltages and quadratically with AC voltages. When applying 5 μs voltage pulses to both crystals, the voltage-induced shift scaled linearly with voltage. For the Y + 36°cut, the voltage-induced shift from applying DC voltages ranged from 10 to 54 ps and 35 to 778 ps for AC voltages at 640 V over the frequency range of 100 Hz-100 kHz. Using the same conditions as the Y + 36°cut, the 0°X-cut crystal sensed a shift of 10-273 ps for DC voltages and 189-813 ps for AC voltage application. For 5 μs voltage pulses, the 0°X-cut crystal sensed a voltage induced shift of 0.250-2 ns and the Y + 36°-cut crystal sensed a time shift of 0.115-1.6 ns. This suggests a frequency sensitive response to voltage where the influence of the crystal cut was not a significant contributor under DC, AC, or pulsed voltage conditions. The measured DC data were compared to a 1-D impedance matrix model where the predicted incremental length changed as a function of voltage. When the voltage source error was eliminated through physical modeling from the uncertainty budget, the combined uncertainty of the sensor (within a 95% confidence interval) decreased to 0.0033% using a Y + 36°-cut crystal and 0.0032% using an X-cut crystal for all the voltage conditions used in this experiment.
Branch, Darren W.; Smith, Gennifer T.; Vreeland, Erika C.; Blakemore, Robert; Alland, David
We have developed a miniature ultrasonic lysing system for the rapid release and extraction of Mycobacterium Tuberculosis (MTB) DNA. The prototype consists of two key sections, a disposable plastic manifold that hold sputum slides and a plastic cartridge with five fluidic DNA extraction channels. The MTB vaccine Bacillus Calmette-Guérin (BCG) was used as a simulant for MTB for all the lysing studies. The slide manifold houses up to five individual sputum slides and is processed by a computer to fill and load the cartridges with sputum suspensions from each slide. The plastic cartridge was developed to facilitate acoustic coupling through the bottom interface such that MTB/BCG can be lysed remotely. The disposable cartridge eliminated cross contamination problems and additional cleaning time. Due to the high power density, only 66 mW was required to lyse microliter BCG samples at the same level as the positive control (i.e. boiling for 30 minutes at 95 °C).
Eliminating spurious modes in Aluminum Nitride (AlN) microresonators improves their insertion loss and quality factor by reducing acoustic energy leakage. Spurious modes that result from transverse wave propagation, termed fine-frequency modes, leak energy and propagate in the electrical busing and appear near the fundamental resonance. Although these modes can be predicted using three-dimensional (3D) finite element methods (FEM) for devices with very short acoustic length (e.g. 1 acoustic wavelength), 3D FEM is very slow and memory intensive when compared to a two-dimensional (2D) simulation. A fast 2D coupling-of-modes (COM) model was developed to predict, identify and implement strategies to suppress the fine-frequency modes.