Biological and Environmental Research (BER) Program

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Catherine Mageeney is seeking a “kill shot” in bacterial pathogens

News Article, January 17, 2023 • Catherine Mageeney, a senior member of Sandia’s technical staff in bioengineering and biotechnology, has expertise in phage biology and genetics with broad applications and implications for scientific research. Phages, or viruses that infect bacteria, are the most numerous and diverse biological-organism in Earth’s biosphere. With approximately 1031 existing phages to be...
Catherine Mageeney in front of Sandia’s Thunderbird logo.

High-quality feedstocks address sustainability challenges associated with rising global demand for protein

News Article, January 23, 2023 • RuBisCO variants increase Methionine and Lysine content. (Graphic courtesy of Sandia Licensing and Technology Transfer.) Ryan Davis, a principal member of Sandia’s technical staff in Bioresource and Environmental Security, and his team developed a high-quality feedstock to address sustainability challenges to meet the growing global demand for protein. RuBisCO (Ribulose-1,5-bisphosphate...
Image of a male scientist looking at a test tube

Secure bioscience design project expands CRISPR molecular toolkit

News Article, January 17, 2023 • The Intrinsic Control for Genome and Transcriptome Editing in Communities (InCoGenTEC) project team, exploiting the CRISPR-associated (CRISPR-Cas) system in bacteria, developed a novel variant of the Cas13 enzyme by fusing it to translation Initiation Factor IF3, enhancing protein expression 21.3-fold above Cas13 alone. InCoGenTEC, led by NTESS for DOE’s Biological...