Taylor Moehling

Biography

Taylor Moehling started at Sandia National Laboratories in Livermore, CA in 2020 as a postdoc and joined a team designing a portable platform to rapidly detect SARS-CoV-2 directly from clinical samples. Other notable projects include characterizing a pathogen-agnostic enrichment technique, designing single-tube multiplexed molecular assays, developing a computational model to predict the effects of genomic mutations on detection assays, and standardizing sequencing protocols for pathogen monitoring in wastewater. Taylor also works with Sandia’s Global Chemical and Biological Security team in Nigeria and with the Systems Analysis group to conceptualize an International Biological Monitoring System. Ultimately, she is interested in both improving the fundamental understanding of and translating molecular assays from the laboratory to the point of need to enable widespread access to accurate detection tools.

Education

Bachelor’s Degree: Biomedical Engineering, University of Wisconsin-Madison

Master’s Degree: Public Health, Purdue University

Doctoral Degree: Biomedical Engineering, Purdue University

Postdoctoral Fellowship: Sandia National Laboratories

Research Interests

Biothreat detection/diagnostics, molecular assays, portable detection/diagnostics, persistence of pathogens in environmental samples, host response biomarkers.

Publications

Moehling, T.J., et al. (2024). Development of a Colorimetric Loop-Mediated Isothermal Amplification Assay for the Detection of Trypanosoma cruzi in Low-Resource Settings. Diagnostics. DOI: 10.3390/diagnostics14111193

Moehling, T.J., et al. (2024). Effects of Single and Multiple Nucleotide Mutations on Loop-Mediated Isothermal Amplification. Analyst. DOI: 10.1039/D3AN01927F

Choi, G., Moehling, T.J., and Meagher, R.J. (2023). Advances in RT-LAMP for COVID-19 Testing and Diagnosis. Expert Review of Molecular Diagnostics. DOI: 10.1080/14737159.2023.2169071

Meyerson, B.E., Moehling T.J., … (2021). Insufficient Access: Naloxone Availability to Laypeople in Arizona and Indiana, 2018. Journal of Health Care for the Poor and Underserved. DOI: muse.jhu.edu/794650

Moehling, T.J., Choi, G., et al. (2021). LAMP Diagnostics at the Point of Care: Emerging Trends and Perspectives for the Developer Community. Expert Review of Molecular Diagnostics. DOI: 10.1080/14737159.2021.1873769

Moehling, T.J., Lee, D.H., et al. (2020). A Smartphone-Based Particle Diffusometry Platform for Sub-Attomolar Detection of Vibrio cholerae in Environmental Water. Biosensors and Bioelectronics. DOI: 10.1016/j.bios.2020.112497

Meyerson, B.E., … Moehling, T.J., … (2020). Feasibility of a Pharmacy-Based Harm Reduction Intervention to Reduce Opioid Overdose, HIV, and Hepatitis C – Indiana. Research in Social and Admin Pharm. DOI: 10.1016/j.sapharm.2019.08.026

Byers, K.M., … Moehling, T.J., … (2019). Versatile Printed Microheaters to Enable Low-Power Thermal Control in Paper Diagnostics. Analyst. DOI:10.1039/c9an01546a

Phillips, E.A., Moehling, T.J., et al. (2019). Microfluidic Rapid and Autonomous Analytical Device (microRAAD) to Detect HIV RNA from Whole Blood Samples. Lab on a Chip. DOI: 10.1039/C9LC00506D

Clayton, K.N., Moehling, T.J., et al. (2019). Particle Diffusometry: An Optical Detection Method for Vibrio cholerae Presence in Environmental Water Samples. Nature Scientific Reports. DOI: 10.1038/s41598-018-38056-7

Phillips, E.A., Moehling, T.J., … (2018). Strand Displacement Probes Combined with Isothermal Nucleic Acid Amplification for Instrument-Free Detection from Complex Samples. Analytical Chemistry. DOI: 10.1021/acs.analchem.8b00269

Zhang, Q., … Moehling, T.J, … (2018). Exposure to Alumina Nanoparticles in Female Mice During Pregnancy Induces Neurodevelopmental Toxicity in the Offspring. Frontiers in Pharmacology. DOI: 10.3389/fphar.2018.00253

Marshall, C., … Moehling, T.J., … (2014). An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins. ACS Chemical Biology. DOI: 10.1021/cb500689g

*indicates co-first author

Patents and Trademarks

Wereley, S.T., … Moehling, T.J. (2022). Methods of measuring structural and functional changes of a biomolecular composition. U.S. Patent 11221287.