The ALEGRA application is targeted at the simulation of high strain rate, magnetohydrodynamic, electromechanic and high energy density physics phenomena for the U.S. defense and energy programs. Research and development in advanced methods, including code frameworks, large scale inline meshing, multiscale lagrangian hydrodynamics, resistive magnetohydrodynamic methods, material interface reconstruction, and code verification and validation, keeps the software on the cutting edge of high performance computing.