Ronald Manginell

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Manager, Nano and Micro Sensors

Ron Manginell manages the Nano and Micro Sensors Department at Sandia National Laboratories, which specializes in miniature sensors and sensor-based systems for a variety of sensing modalities including chemical, biological, radiological, nuclear, and explosives. These sensors and systems can be built into wearable, handheld, UAV, or fixed/installed formats. The department has a strong emphasis on nano, micro, and mesoscale fabrication including the capability to integrate custom electronics developed in the MESA cleanroom complex. To support the team’s chemical vapor detection effort, they are developing a state of the art Test and Evaluation system to challenge a variety of sensors/systems. In biological detection they have acoustic- and electrochemical-based wearable systems for cell lysis and highly specific and sensitive detection of DNA, RNA, proteins, and metabolites. Sandia is a recognized leader in acoustic-based sensors and lysis and in integrated microneedle and sensor technology. The department also has state-of-the-art microbiology capabilities to aid in biological sensor development. Their technologies are designed to be non-invasive or minimally invasive and easy to use in the field or at the point of care.

Education

Bachelor’s Degree: Physics, Rochester Institute of Technology

Doctoral Degree: Physics, University of New Mexico with research performed at Sandia National Laboratories

Postdoctoral Fellowships: Microsensors Department, Sandia National Laboratories

Selected Publications

R. Jock et al, “A Silicon metal-oxide-semiconductor electron spin-orbit qubit,” Nature Communications, 9, 1768 (2018) doi:10.1038/s41467-018-04200-0.

C. Sillerud et al, "Characterization of chemical contaminants and their spectral properties from an atmospheric pressure ns-pulsed microdischarge in neon,"  Physics of Plasmas, 24 (2017) 10.1063/1.4977448.

K. E. Achyuthan et al, “Volatile Metabolites Emission by In Vivo Microalgae—An Overlooked Opportunity?,” Metabolites 2017, 7(3), 39.

P.D.D Schwindt et al, “A highly miniaturized vacuum package for a trapped ion atomic clock,” Review of Scientific Instruments 87 (5):053112 · May 2016.

M. Singh et al, “Electrostatically defined silicon quantum dots with counted antimony donor implants,” Applied Physics Letters 108(6):062101 · February 2016.

C. D. Mowry et al, “Pulsed Discharge Ionization Detector for Highly Sensitive Aquametry,” Analytical Sciences, 32 (2016) 177-182.

R. P. Manginell, et al, “Development of a Mesoscale Pulsed Discharge Helium Ionization Detector for Portable Gas Chromatography,” Analytical Sciences, 31 (2015) 1183-1188.

T. Lipe., et al., “New Technologies to Improve AC-DC Difference Measurements at NIST,” The Journal of Measurement Science, 9 (2014), pp 52-58.

J. M. Anderson, et al., “Isothermal Mass Flow Measurements In Microfabricated Rectangular Channels Over a Very Wide Knudsen Range,” J. Micromech. & Microeng., 04/2014; 24(5):055013.

B. Harmon, et al., “Identification of Critical Amino Acids within the Necleoprotein of Tacaribe Virus Imortant for Anti-Interferon Activity,” J. Biological Chem., 288 (2013) 8702-8711.

E. S. Schares, et. al., “Three-Dimensional Modeling of DNA Kinetics and Mass Transport as Functions of Temperature in a Microchannel,” Electrophoresis, 34 (2013) 2112-2119.

R. P. Manginell, et. al., “Diagnostic Potential of the Pulsed Discharge Ionization Detector Using Pathogenic Micobacterial Volatile Biomarkers,” J. Breath Res. 7 (2013) 037107.

R. P. Manginell, et. al., “In Situ Dissolution/Deposition of Ytterbium in Microhotplate Wells for a Miniaturized Atomic Clock,” Optics Express, 20 (2012) 24650-24663.

R. S. Johnson, et. al., “Thermally-Activated Pentanol Delivery from Precursor Poly(p-phenylenevinylene)s for MEMS Lubrication,” Molecular Rapid Communications, 18 JUL 2012, DOI: 10.1002/marc.201200325.

M. A. Gallis et al., “Direct simulation Monte Carlo-based expressions for the gas mass flow rate and pressure profile in a microscale tube,” Phys. Fluids 24 012005.

R.P. Manginell, et. al., “A Materials Investigation of a Phase-Change Micro-Valve for Greenhouse Gas Collection etc.,” Rev. Sci. Instr., Cover Article, 83 031301 (2012).

R. P. Manginell, et. al.,”Monolithically-Integrated MicroGC,” Sensors 2011, 11, 6517-6532.

C. D. James, et. al.,  “Nuclear Translocation Kinetics of NF-B in Macrophages Challenged with Pathogens in a Microfluidic Platform,” Biomedical Microdevices, 11 (2009) 693-700.

R. P. Manginell, et. al., “Mass Sensitive Microfabricated Chemical Preconcentrator,” J. Microelectromechanical Systems, 17 (2008) 1396-1407.

R. P. Manginell, et. al., “ Two-Dimensional Modeling and Simulation of Mass Transport in Microfabricated Preconcentrators,” IEEE Sensors Journal, 7 (2007) 1032-1041.

D. Cruz, et. al., “Microfabricated Thermal Conductivity Detector for the Micro-ChemLab,” Sensors and Actuators B, 121 (2007) 414-422.

P. R. Lewis, et. al., “Recent Advancements in the Gas Phase Microchemlab,” IEEE Sensors Journal, 6 (2006) 784-796.

J. M. Bauer, et. al., “Nanoscale Transport and Assembly with Motor Proteins and Microtubules,” Royal Society of Chemistry Special Publications, 296 (2005) 18-20.

Book Chapter “Integrated Chemical Sensors in CMOS Technology”, By A. Hierlemann, Springer-Verlag, December, 2004.

D.L. Huber, et. al., “Programmed Adsorption and Release of Proteins in a Microfluidic Device,” Science, 301 (2003) 352-354.

B. Bunker, et. al., "Incorporation of Bioactive Materials into Integrated Systems," Proc. Soc. Photo-Opt. Instrum. Eng., 5220 (2003) 28-36.

T. F. Wunsch, et al., “Fabrication Process For Planar Thin-Film Multijuction Thermal Converters,” IEEE Trans. Instrumentation and Measurement, 50 (2001) 330-332.

Book Chapter “Microbridge Combustible Gas Sensor” in “Microsystem Design” by S. D. Senturia, Kluwer, 2001, pp. 629-649.

D. L. Kendall, et. al., “Micromirror Arrays Using KOH:H20 Micromachining of Silicon for Lens Templates and Geodesic Lenses etc.,” Optical Engineering 33, (1994) 3578-3588.

R. P. Manginell, et. al., “Novel Micro-Preconcentrators for Chemical Warfare Agents, Explosives and Water Surety,” SAND2004-6316, December 2004.