Reportable, analytical results of biological-sample collection efforts are based on assumptions of near 100% collection–and–extraction transfer efficiency. However, the transfer efficiencies of current methods used to collect and extract biological samples from complex surfaces have never been evaluated.
To address this issue, Sandia conducted a robust scientific and statistical evaluation of current surface sample collection and extraction methods for anthrax spores. The goal was to determine if collection efficiencies are a function of surface concentration and to determine the method limits of detection.
The results of our study are being used by the National Institute of Occupational Safety and Health (NIOSH) to modify portions of its anthrax spore sampling methods.
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