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Research in Microfluidics 

MicroChemLab
MicroChemLab™ biodetector

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Research in Microfluidic Transport at Sandia National Laboratories

Reversed Chromatography ON for
Chem/Bio Warfare Agent Detection – Chip Electrochromatography on Porous Polymer Monoliths

Porous polymer monoliths (PPMs) for capillary electrochromatography are an attractive alternative to coated silica beads. The channels are filled with a solution of monomer using hydrostatic pressure and capillary action, so no pressure attachments are necessary.

The PPM forms during the polymerization/phase-separation process to create a continuous monolithic material. The UM-initiated porous polymer monolith is formed in situ on the chip in minutes. Once polymerized, no frits are required.



Chip Electrochromatography :
Isocratic Separation of 13 polycyclic aromatic hydrocarbons

Electrokinetically Generated Solvent Gradients in Chips Filled With a UV-Initiated Porous Monolith for Reversed - Phase CEC

References:

Ngola et al., Porous Polymer Monoliths as Separation Media for CEC Analytical Chemistry; 2001; 73(5); 849-856., Y. Fintschenko, W.-Y. Choi, S. M. Ngola, T. J. Shepodd, Fresenius Journal 371 (2001) 174 .

For Further Information Contact: Malin Young