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Research in Microfluidics 

MicroChemLab
MicroChemLab™ biodetector

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Research in Microfluidic Transport at Sandia National Laboratories

Biotoxin Detection
Using Parallel Separation Arrays

The biotoxin device utilizes micro-scale liquid-phase chromatography and capillary electrophoresis together with laser-induced fluorescence (LIF) detection to provide sensitive analyses at low nanomolar concentration levels.

A two-channel device has been developed and tested which utilizes capillary zone electrophoresis and capillary gel electrophoresis to provide orthogonal analyses of protein mixtures.

Sandia's µChemLab™/CB device performs fully automated parallel channel analysis for protein biotoxins


Gen2 Biotoxin Detection Box
gen chip
Chip

Miniature blue diode lasers
provide fluorescence
excitation light

Microfluids are manipulated using
high voltage control
Fluorescently-tagged proteins  are separated "on chip" in fused silica substrates using capillary zone electrophoresis (CZE) and capilary gel electrophoresis (CGE). Data analysis software inentifies and quantitates protein biotoxins.
Fluorescently-tagged proteins are separated "on chip" in fused silica substrates using capillary zone electrophoresis (CZE) and capilary gel electrophoresis (CGE). Data analysis software inentifies and quantitates protein biotoxins.

For Further Information Contact: Malin Young