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MICA logo. Microscale Immune and Cell Analysis (MICA), Studying immunity - one cell at a time.

MICA (formerly MISL) Publications, December 2008

MICA Platform and Detection Systems

  • Srivastava N, Brennan JS, Renzi RF, Wu MY, Branda SS, Singh AK, Herr AE. Fully Integrated Microfluidic Platform Enabling Automated Phosphoprofiling of Macrophage Response. Analytical Chemistry 81, 3261-3269 (2009).
  • Boas, G. (2008). Sorting it all out: Optical forces enable cell sorting with infectious agents. Biophotonics Research [Online]. August 2008.
  • James, CD, N Reuel, ES Lee, RV Davalos, SS Mani, A Carroll-Portillo, R Rebeil, A Martino, C Apblett. (2008). Impedimetric and optical interrogation of single cells in a microfluidic device for real-time viability and chemical response assessment. Biosensors and Bioelectronics 23:845–861.
  • Patel, KD, TD Perroud. (in preparation). The microflow cytometer. Optical Sorters. Pan Stanford Publishing: Hackensack, NJ. To be published in May 2009.
  • Perroud, TD, JN Kaiser, JC Sy, TW Lane, CS Branda, AK Singh, KD Patel. (2008). Microfluidic-based cell sorting of Francisella tularensis infected macrophages using optical forces. Analytical Chemistry 80:6365–6372.
  • Perroud, TD; Meagher RJ; Kanouff, MP; Renzi, RF; Wu, M; Singh, AK; Patel, KD. Isotropically Etched Radial Micropore for Cell Concentration, Immobilization, and Picodroplet Generation. Lab on a Chip 9, 507-515 (2009). Featured on journal back cover.
  • Pizarro, SA, P Lane, TW Lane, E Cruz, B Haroldsen, VA VanderNoot. (2007). Bacterial characterization using protein profiling in an integrated microchip separations platform. Electrophoresis 28:4697–4704.
  • Sinclair, MB, DM Haaland, JA Timlin, HDT Jones. (2006). Hyperspectral confocal microscope. Applied Optics 45:6283–6291.
  • Stachowiak, JC, EE Shugard, BP Mosier, RF Renzi, PF Caton, SM Ferko, JL Van de Vreugde, DD Yee, BL Haroldsen, VA VanderNoot. (2007). Autonomous microfluidic sample preparation system for protein profile-based detection of aerosolized bacterial cells and spores. Analytical Chemistry 79:5763–5770.

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Related Publications by Subject Area

Computational Biology

  • Faulon, J-L, M Misra, S Martin, K Sale, R Sapra. (2008). Genome scale enzyme-metabolite and drug-target interaction predictions using the signature molecular descriptor. Bioinformatics 24:225–233.
  • Gray, GA, PJ Williams, WM Brown, J-L Faulon, KL Sale. (2008). Disparate data fusion for protein phosphorylation prediction. Annals of Operations Research, Online First. April 29, 2008.
  • Joo, J, S Plimpton, S Martin, L Swiler, A Slepoy, J-L Faulon. (2007). Sensitivity analysis of computational model of the IKK-NF-κB-IκBα-A20 signal transduction network. Annals of the New York Academy of Sciences 1115:221–239.
  • Martin, S, Z Zhang, A Martino, J-L Faulon. (2007). Boolean dynamics of genetic regulatory networks inferred from microarray time series data. Bioinformatics 23:866–874.
  • Van Benthem, MH, MR Keenan. (2008). Tucker1 model algorithms for fast solutions to large PARAFAC problems. Journal of Chemometrics 22:345–354.
  • Van Benthem, MH, MR Keenan, R Davis, P Liu, HDT Jones, DM Haaland, MB Sinclair, AR Brasier. (2008). Trilinear analysis of images obtained with a hyperspectral imaging confocal microscope. Journal of Chemometrics 22:491–499.

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Microfluidics

  • Fruetel, JA, RF Renzi, VA VanderNoot, J Stamps, BA Horn, JAA West, S Ferko, R Crocker, CG Bailey, D Arnold, B Wiedenman, W-Y Choi, D Yee, I Shokair, E Hasselbrink, P Paul, D Rakestraw, D Padgen. (2005). Microchip separations of protein biotoxins using an integrated handheld device. Electrophoresis 26:1144–1154.
  • Fruetel, JA, JAA West, BJ Debusschere, K Hukari, TW Lane, HN Najm, J Ortega, RF Renzi, I Shokair, VA VanderNoot. (2008). Identification of viruses using microfluidic protein profiling and Bayesian classification. Analytical Chemistry, Article ASAP. November 4, 2008.
  • Meagher, RJ, YK Light, AK Singh. (2008). Rapid, continuous purification of proteins in a microfluidic device using genetically engineered partition tags. Lab on a Chip 8:527–532.
  • Reichmuth, DS, SK Wang, LM Barrett, DJ Throckmorton, W Einfeld, AK Singh. (2008). Rapid microchip-based electrophoretic immunoassays for the detection of swine influenza virus. Lab on a Chip 8:1319–1324.
  • Renzi, RF, J Stamps, BA Horn, S Ferko, VA VanderNoot, JAA West, R Crocker, B Wiedenman, D Yee, JA Fruetel. (2004). Hand-held microanalytical instrument for chip-based electrophoretic separations of proteins. Analytical Chemistry 77:435–441.
  • Sommer, G, AK Singh, AV Hatch. (2008). On-chip isoelectric focusing using photopolymerized immobilized pH gradients. Analytical Chemistry 80:3327–3333.
  • Stachowiak, JC, EE Shugard, BP Mosier, RF Renzi, PF Caton, SM Ferko, JL Van de Vreugde, DD Yee, BL Haroldsen, VA VanderNoot. (2007). Autonomous microfluidic sample preparation system for protein profile-based detection of aerosolized bacterial cells and spores. Analytical Chemistry 79:5763–5770.
  • VanderNoot, V. (2007). Portable bioagent detection systems for national security applications. Department of Homeland Security, 2007 Homeland Security Conference. Monterey, CA, August 21–24.
  • VanderNoot, V, D Curtis, P Lane, T Lane. (2007). Development of a portable and automated electrophoresis-based system for in-field toxin detection: HABLab. PacRim 2007, Pacific Rim Shellfish Conference. San Diego, CA, April 22–23.
  • VanderNoot, V et al. (2006). Integrated and automated sample preparation systems for aerosol and water monitoring applications. 2nd National Conference on Environmental Sampling and Detection for Bio-Threat Agents. New York, NY, October 25–27.
  • Vermaas, WFJ, JA Timlin, HDT Jones, MB Sinclair, LT Nieman, S Hamad, DK Melgaard, DM Haaland. (2008). In vivo hyperspectral confocal fluorescence imaging to determine pigment localization and distribution in cyanobacterial cells. Proceedings of the National Academies of Sciences of the United States of America 105:4050–4055.

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RapiDx

  • Meagher, RJ, AV Hatch, RF Renzi, AK Singh. (2008). An integrated microfluidic platform for sensitive and rapid detection of biological toxins. Lab Chip, 8:2046–2053.
  • Hatch AV, AE Herr, DJ Throckmorton, JS Brennan, AK Singh. (2006). Integrated preconcentration SDS-PAGE of proteins in microchips using photopatterned cross-linked polyacrylamide gels. Analytical Chemistry 78:4976–4984.
  • Herr, AE, AV Hatch, DJ Throckmorton, HM Tran, JS Brennan, WV Giannobile, AK Singh. (2007). Microfluidic immunoassays as rapid saliva-based clinical diagnostics. Proceedings of the National Academy of Sciences of the United States of America 104:5268–5273.
  • Wang, Y-C, AK Singh, AV Hatch. (2008). Ultra-rapid sample preconcentration under slant field using high-aspect-ratio nanoporous membranes. Proceedings of MicroTAS 2008, The Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences, San Diego, CA. October 12–16.

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